Anticancer Activity and Chemical Composition of Leaf Essential Oil from Solidago canadensis L. in China
The essential oil was obtained at yield of 0.30% by hydrodistillation from fresh leaf tissue of Solidago canadensis L. collected from Zhejiang Province, China. GC and GC/MS analysis identified 46 components, representing 94.6% of the leaf oil. The main components were (-)germacrene D (28.4%), bornyl acetate (9.2%), D-Limonene (5.0%). The essential oil was tested for cytotoxic activities against three tumor cell lines. The inhibitory concentrations of the essential oil at 50% effect level (IC50) were 68.1 μg/ml for SMMC-7721, 71.4 μg/ml for SGC-7901, and 156.9 μg/ml for Hala, respectively.
Weiguo Pan, Jianxing Ren and Yongguang Li
D. Q. Li et al., "Anticancer Activity and Chemical Composition of Leaf Essential Oil from Solidago canadensis L. in China", Advanced Materials Research, Vols. 347-353, pp. 1584-1589, 2012