Anticancer Activity and Chemical Composition of Leaf Essential Oil from Solidago canadensis L. in China

Abstract:

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The essential oil was obtained at yield of 0.30% by hydrodistillation from fresh leaf tissue of Solidago canadensis L. collected from Zhejiang Province, China. GC and GC/MS analysis identified 46 components, representing 94.6% of the leaf oil. The main components were (-)germacrene D (28.4%), bornyl acetate (9.2%), D-Limonene (5.0%). The essential oil was tested for cytotoxic activities against three tumor cell lines. The inhibitory concentrations of the essential oil at 50% effect level (IC50) were 68.1 μg/ml for SMMC-7721, 71.4 μg/ml for SGC-7901, and 156.9 μg/ml for Hala, respectively.

Info:

Periodical:

Advanced Materials Research (Volumes 347-353)

Edited by:

Weiguo Pan, Jianxing Ren and Yongguang Li

Pages:

1584-1589

DOI:

10.4028/www.scientific.net/AMR.347-353.1584

Citation:

D. Q. Li et al., "Anticancer Activity and Chemical Composition of Leaf Essential Oil from Solidago canadensis L. in China", Advanced Materials Research, Vols. 347-353, pp. 1584-1589, 2012

Online since:

October 2011

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$35.00

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