Subtle reservoir is an important area of hydrocarbon exploration in Qiongdongnan basin. The reservoir hydrocarbon-bearing potential is one of the cores of this research, and the geophysical technology is the main research tool. In this paper, AVO, AVD, DR and seismic attenuation gradient techniques are carried out to evaluate the hydrocarbon-bearing ability. Taking the JY area of eastern Qiongdongnan basin as a case study, the results show that the characteristics of gas-bearing reservoir in JY area are the 3rd AVO anomaly, high AVD and DR, and low attenuation gradient. Furthermore, multi-information fusion technique is used to qualify the gas resource scale and provide decision-making advice for the future exploration. It shows that the seismic anomaly sand body of the first member of Sanya Formation in JY area has large gas resource potential and good exploration prospect.