Synthesis of Strontium-Doped Hydroxyapatite Powder via Sol-Gel Method
Strontium is one of metallic elements found in bones and teeth. It is an essential substance in preventing osteoporosis and has the ability to regenerate, preserve, and even restore bone growth. Synthesizing Sr-doped HA powder is of great importance accordingly. Here we present Sr-doped HA powders prepared via sol-gel procedure using calcium nitrate and diammonium hydrogen phosphate as the precursors. Strontium nitrate was used as the dopant source, and its concentration was varied from 2~15 %. An ammoniacal solution was heated until a white gel was obtained. The obtained gel was then dried and subsequently subjected to 900°C calcination. Characterization on the obtained powder was conducted using XRD, FTIR, and FESEM. XRD measurement had shown that the powder contained hydroxyapatite phase only. Morphological evaluation by FESEM measurement shows that the particles of the Sr -doped HA agglomerates are globular in shape with an average size of 1-2 µm in diameter. Meanwhile, the primary particles have a diameter of 50-150 nm in average. It is likely Sr has played an important role as a calcination or sintering additive, causing more progressive densification of particles.
Alan K.T. Lau, J. Lu, Vijay K. Varadan, F.K. Chang, J.P. Tu and P.M. Lam
I. Sopyan et al., "Synthesis of Strontium-Doped Hydroxyapatite Powder via Sol-Gel Method", Advanced Materials Research, Vols. 47-50, pp. 928-931, 2008