Study of Microwave Synthesis of 2 - Hydroxy Phosphono Acetic Acid Process


Article Preview

This research introduced microwave synthesis process of HPAA (2-hydroxyphosphonoacetic acid) which was synthesized from glyoxylate and phosphorous acid. The optimized technological conditions was defined by orthogonal experiment. The mass proportion of phosphorous and glyoxylate was 1:1.2, catalyst mass was 1g, 95°C, 25min, and its yield rate was more than 90%. The molecular structure of product was characterized by IR spectrogram analysis. This method was simple、economical and practical.



Advanced Materials Research (Volumes 581-582)

Edited by:

Jimmy (C.M.) Kao, Wen-Pei Sung and Ran Chen




Q. Y. Zhang et al., "Study of Microwave Synthesis of 2 - Hydroxy Phosphono Acetic Acid Process", Advanced Materials Research, Vols. 581-582, pp. 219-222, 2012

Online since:

October 2012




[1] F.C. Jia, Z.T. Li, Q.Y. Dong, Present situation and development of scale inhibitor for industrial circulating cooling water, J. Industrial Water Treatment. 26 (2006) 12-14.

[2] Q. Sun, X.J. Shi, F.H. Wang, Research progress in water treatment agent with phosphorus, J. Liaoning Chemical Industry. 36 (2007) 276-277.

[3] L. Li, Y.L. Wang, Y.L. Cheng, Y. Bai, Quality inspection of 2- hydroxyphosphonoacetic acid (HPAA) product, J. Industrial Water Treatment. 28 (2008) 73-76.

[4] Q.K. Mo, J. Lu, J. Yuan, Study on determination method of phosphorous acid, J. Technology & Development of Chemical Industry. 38 (2009) 33-35.