Study of Microwave Synthesis of 2 - Hydroxy Phosphono Acetic Acid Process
This research introduced microwave synthesis process of HPAA (2-hydroxyphosphonoacetic acid) which was synthesized from glyoxylate and phosphorous acid. The optimized technological conditions was defined by orthogonal experiment. The mass proportion of phosphorous and glyoxylate was 1:1.2, catalyst mass was 1g, 95°C, 25min, and its yield rate was more than 90%. The molecular structure of product was characterized by IR spectrogram analysis. This method was simple、economical and practical.
Jimmy (C.M.) Kao, Wen-Pei Sung and Ran Chen
Q. Y. Zhang et al., "Study of Microwave Synthesis of 2 - Hydroxy Phosphono Acetic Acid Process", Advanced Materials Research, Vols. 581-582, pp. 219-222, 2012