Biopolymer Encapsulation of CdTe Quantum Dot for In Vitro Controlled Drug Delivery Release of 6-Mercaptopurine
Alginate biopolymer stabilized CdTe quantum dot (QD) was prepared and it was encapsulated with folic acid conjugated chitosan for controlled drug delivery of anticancer drug 6-mercaptopurine (6-MP). In addition to alginate, chitosan enhances the stability of QD. Also, in addition to chitosan, alginate binds to the drug leading to enhance the loading efficiency of the resulting drug carrier. The drug release profile of the carrier was investigated by in-vitro. The present study has shown that this drug carrier is feasible for drug delivery and will be important beneficiary for cancer therapy.
D. Rajan Babu
S. Parani et al., "Biopolymer Encapsulation of CdTe Quantum Dot for In Vitro Controlled Drug Delivery Release of 6-Mercaptopurine", Advanced Materials Research, Vol. 584, pp. 258-262, 2012