Simulation of Left Heart-Arterial System Using Electronic Model


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An analog circuit model of the left heart-arterial coupling system has been designed to study the behavior of the left heart-arterial system. Then the state variable method was used to analyze the circuit model and establish the mathematical model. We use Matlab/Simullink tool to simulate the mathematical model. Some important parameters of the left heart circulation system, such as left ventricular (LV) pressure, left atrium pressure, aortic pressure, aortic flow, LV end-diastolic volume and end-systolic volume, can be obtained. The results are matched the actual physiological, which suggests that the model presented in this paper provides a useful tool to investigate the functional status of left heart-arterial system.



Advanced Materials Research (Volumes 588-589)

Edited by:

Lawrence Lim




X. Y. Huang et al., "Simulation of Left Heart-Arterial System Using Electronic Model", Advanced Materials Research, Vols. 588-589, pp. 1292-1295, 2012

Online since:

November 2012




[1] X. Li, J. Bai, S. Cui, and S. Wang: Computers in biology and medicine. 32(2002), p.345.

[2] S. G. Shroff, J. S. Janicki, and K. T: Weber, American Journal of Physiology-Heart and Circulatory Physiology. 249(1985), p. H358.

[3] H. Suga, and K. Sagawa: Circulation research. 35(1974), p.117.

[4] S. M. Toy, J. Melbin, and A. Noordergraaf: Biomedical Engineering, IEEE Transactions on. BME-32(1985), p.174.

[5] K. Morishita, and M. Kambe: Medical and Biological Engineering and Computing. 33(1995), p.699.

[6] N. Stergiopulos, B. E. Westerhof, and N. Westerhof: American Journal of Physiology-Heart and Circulatory Physiology. 276(1999), p. H81.

[7] Z. R. Liu: Elastic chamber theory and its application in cardiovascular system analysis (Science Press, Beijing 1987).

[8] D. J. Tsalikakis, D. I. Fotiadis, and D. Sideris: Comput. Cardiol. 30(2003), p.445.

[9] P. Segers: Journal of engineering mathematics 47(2003), p.185.

[10] Y. Yang, X. M. Wu, and L. L. Chen: Chinese Journal of Medical Physics. 22(2005), p.730.

[11] E. Kuh, and R. Rohrer: Proceedings of the IEEE. 53(1965), p.672.

[12] C. Guyton, and J. E. Hall: Textbook of medical physiology (Saunders Philadelphia, PA 1991).

[13] L. M. Yue: Physiology ( science press, Beijing 2002).