Study of Porous Hydroxyapatite/Chitosan Bioceramics for Bone Implantation
hydroxyapatite/Chitosan bioceramics were fabricated by combining in-situ chemical synthesis and freeze drying method, using (NH4)2HPO4, Ca(NO3)2·4H2O, and chitosan(CS) as raw materials. The effect of freezing temperatures, solid loading and freeze-drying time on microstructures of hydroxyapatite/Chitosan bioceramics was studied. The microstructures of the fabricated porous bioceramics were investigated by means of Fourier transform infrared spectroscopy (FT-IR) and scanning electron microscopy (SEM). The results showed that the hydroxyapatite/Chitosan bioceramics have interconnected porous structures from several microns to 200um, more suitable to bone tissue implantation. In addition, the porous structures are affected by freezing temperature.
F. Wang et al., "Study of Porous Hydroxyapatite/Chitosan Bioceramics for Bone Implantation", Advanced Materials Research, Vol. 590, pp. 87-90, 2012