Effect of Psoraleae Gel on Vitiligo Animal Pathological Pattern
Objective: Explore the effect of psoraleae gels external use on vitiligo guinea pig, to prove psoraleae gel can promote the formation of melanin guinea pig skin like psoraleae injection. Methods: Using chemical decolorization to establish vitiligo animal models, treatment by psoraleae gel, observation the effect of high, moderate and low dose of psoraleae gel external use in vitiligo guinea pig serum ChE activity and MDA level, skin pathological changes and the sum total of skin melanin granules. Results: Compared with model group, high, moderate dose psoraleae gel group can significantly improve the serum ChE activity, on vitiligo mode, High, moderate dose psoraleae gel group can significantly improve the serum ChE activity and significantly reduce serum MDA level, high, moderate and low dose psoraleae gel group were significantly promote the guinea pig skin melanin formation and the sum total of melanin granules increased significantly. Conclusion: Psoraleae gel treatments of vitiligo guinea pigs have a very good role; this experiment can show psoraleae gel can be used in the clinical treatment of vitiligo.
Yiqian Wang, Hongzong Si, Yimin Su and Peilong Xu
M. S. Miao et al., "Effect of Psoraleae Gel on Vitiligo Animal Pathological Pattern", Advanced Materials Research, Vols. 850-851, pp. 1263-1266, 2014