Molecular Ion Channels; Electrodiffusion in R3
Ion transport across the membrane of the living cell (molecular ion channels) is a critical process, e.g., the triggering of nerve cells and heart muscle cells is coupled with mechanisms controlled by ion diffusion (electrodiffusion). Although the process is described by the century old Nernst- Planck-Poisson system of equations, it is not well understood and a clear understanding of how the interaction between channel and ions affects the flow is still missing. We present a three-dimensional model of the molecular channel. An appropriate quantitative description of the ion transport process allows proper explanation of molecule channel interactions (e.g. the ions flow for a given concentration gradient should depend on the potential and other parameters describing the interaction, i.e. asymmetric transport). We show the simulation of the stationary electrodiffusion in the ion channel showing radial symmetry.
Andreas Öchsner, Graeme E. Murch, Ali Shokuhfar and João M.P.Q. Delgado
B. Bożek et al., "Molecular Ion Channels; Electrodiffusion in R3", Defect and Diffusion Forum, Vols. 297-301, pp. 1469-1474, 2010