In this study, the reliability analysis of the low pressure steam turbine blade was performed using the Monte Carlo simulation considering variations of applied stress and strength. Applied stress under the service condition of steady state was obtained by finite element analysis. The fatigue strength under rotating bending load was evaluated by the staircase method. The most appropriate probabilistic distribution of the fatigue strength is 3-parameter Weibull distribution, which is determined by the comparative analysis. The failure probability under various loading conditions was derived from the strength-stress interference model.