Microstructure and Bio-Mineralization Behavior of the Sol-Gel Derived Bioactive Materials

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The biomaterials in system CaO-P2O5-SiO2 were synthesized via sol-gel method. The biomaterials can be applied to bone reparation and bone tissue engineering scaffolds The nano-pore structure, degradability, bioactivity and bio-mineralization characteristic of the biomaterials were investigated in details using XRD, SEM/EDX, FTIR, BET and DSC/TG techniques. It was indicated that the sol-gel derived biomaterials have a higher bioactivity than that of the melt derived bioactive glasses or glass-ceramics. It just takes 4-8 hours for HCA to form on the surface of the sol-gel samples in SBF solution at 37°C. The spherical HCA crystal clusters formed on the surface of the sol-gel derived samples immersed in SBF for 8 hours have a low crystallinity. Owing to their interconnected nano-sized pores, the sol-gel samples possess much higher surface areas and the hydrous porous SiO2 gel layer containing a great amount of ºSi-OH groups can be rapidly formed on the biomterials’ surface through a quick ion exchange between H3O+ in the solution and Ca2+ in the surface of the materials. ºSi-OH groups can play a very important role in inducing formation of HCA. They make the material surfaces electronegative, which resulted in a double electrode layer formed between the samples surface and SBF solution. The double electrode layer is in favor of formation of HCA on the surface of the materials.

Info:

Periodical:

Key Engineering Materials (Volumes 280-283)

Edited by:

Wei Pan, Jianghong Gong, Chang-Chun Ge and Jing-Feng Li

Pages:

1609-1612

DOI:

10.4028/www.scientific.net/KEM.280-283.1609

Citation:

X. F. Chen et al., "Microstructure and Bio-Mineralization Behavior of the Sol-Gel Derived Bioactive Materials", Key Engineering Materials, Vols. 280-283, pp. 1609-1612, 2005

Online since:

February 2007

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Price:

$38.00

[1] L.L. Hench: Biomaterials. Vol. 19 (1998), p.1419.

[2] L.L. Hench, R.J. Splinter, W.C. Allen and T.K. Greenlee: J. Biomed. Mater. Res. Symp. Vol. 2 (1971), p.117.

[3] L.L. Hench and J. Wilson: An introduction to bioceramics (Advanced series in ceramics-Vol. 1), ed. Hench LL and Wilson J, Vol17(1993), p.41.

[4] L.L. Hench: Bioceramics, ed. Giannini S, Morni A. Vol. 13 (2000), p.575.

[5] L.L. Hench: J. Am. Ceram. Soc. Vol. 74 (1991), p.1487.

[6] S.B. Cho, K. Nakanishi, T. Kokubo, et al.: J. Biomed. Mater. Res. Vol. 33 (1996), p.141.

[7] P. Li, K. de Groot and T. Kokubo: J. Sol-Gel Sci. Technol. Vol. 7 (1996), p.127.

[8] L.L. Hench: Bioceramics, ed. Giannini S, Morni A. Vol. 13 (2000), p.575.

[9] D.C. Greenpan, J.P. Zhong, G.P. LaTorre and M. Booher: Transactions of the 23rd annual Meeting of the Society for Biomaterials. New Orleans, La: Society for Biomaterials, (1997).

[10] M.M. Pereira, A.E. Clark and L.L. Hench: J. Biomed. Mater. Res. Vol. 18 (1994), p.693.

[11] L.L. Hench and J.M. Polak: Science Vol. 295 (2002), p.1014.

[12] P. Li and F. Zhang: J. Non-Cryst. Solids Vol. 119 (1990), p.112.

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