Injectability of a Macroporous Calcium Phosphate Cement


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In this work an injectable and self setting calcium phosphate/albumen foam is developed. The effect of both the amount of albumen and the particle size of the starting a-tricalcium phosphate (a-TCP) powder on the injectability of the cement paste is studied. X-ray diffraction (XRD) and infrared (IR) analysis of the samples reveal that the hydrolysis of a-TCP to calcium deficient hydroxyapatite (CDHA) is not affected by the addition of albumen. A foamed structure formed by spherical pores with diameters between 100 and 500 µm is observed by SEM. This porous structure is maintained after injection of the paste, although some deformation of the pores is produced due to the extrusion process. The injectability of the cements is increased by the presence of albumen as compared with cements prepared in the same conditions but without foaming agent.



Key Engineering Materials (Volumes 284-286)

Main Theme:

Edited by:

Panjian Li, Kai Zhang and Clifford W. Colwell, Jr.




J.A. Delgado et al., "Injectability of a Macroporous Calcium Phosphate Cement", Key Engineering Materials, Vols. 284-286, pp. 157-160, 2005

Online since:

April 2005




[1] S. Takagi and L.C. Chow: J. Mat. Sci.: Mat. Med. Vol 12 (2001), p.135.

[2] M. Bohner, Key Engineering Materials Vols. 192-195 (2001), p.765.

[3] Y. Yin, F. Ye, S. Cai, K. Yao, J. Cui and X. Song: J. Mat. Sci.: Mat Med. Vol 14 (2003), p.255.

[4] A. Almirall, J.A. Delgado, M.P. Ginebra and J.A. Planell: Key Engineering Materials Vols. 254- 256 (2004), p.253.

[5] M.P. Ginebra, E. Fernández, E.A.P. De Maeyer, R.M.H. Verbeeck, M.G. Boltong, J. Ginebra, F.C.M. Driessens and J.A. Planell: J. Dent. Res. Vol. 76 (1997), p.905.


[6] M.P. Ginebra, F.C.M. Driessens, J.A. Planell: Biomaterials Vol. 25 (2004), p.3453.

[7] I. Khairoun, M.G. Boltong, F.C.M. Driessens and J.A. Planell: J. Mat. Sci.: Mat Med. Vol. 9 (1998), p.425.

[8] D. Weaire, S. Hutzler, The physics of foams, Oxford University Press, Oxford, UX (1999).