Adsorption Isotherm of Sodium Ampicillin onto Dense and Porous Hydroxyapatite
The adsorption behaviour of sodium ampicillin to dense and porous hydroxyapatite as been extensively studied through the obtention of an adsorption isotherm. This isotherm was produced at body temperature, and a wide range of antibiotic solutions was used. The adsorption behaviour was measured by UV spectroscopy. The shape of the isotherm for the two forms of the material, dense and porous, indicates that the adsorption behaviour of the antibiotic seems to be different; however, this is due to the adsorption taking place within the pores of the porous material, thus showing a larger amount of antibiotic adsorbed.
Panjian Li, Kai Zhang and Clifford W. Colwell, Jr.
A.C. Queiroz et al., "Adsorption Isotherm of Sodium Ampicillin onto Dense and Porous Hydroxyapatite", Key Engineering Materials, Vols. 284-286, pp. 387-390, 2005