Porous HA Scaffolds for Drug Releasing


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Dense and porous hydroxyapatite materials aimed at being used in controlled drug delivery, were characterised and studied in order to evaluate their ability to adsorb and release sodium ampicillin in a controlled manner, as a model for a drug delivery system, potentially applicable associated to surgery for the treatment of bone defects. These porous materials should also have adequate mechanical strength to withstand manipulation and sculpturing in surgery room. Adsorption and release profiles were obtained for a range of porous materials, leading to higher adsorption rates and more adequate release profiles than for dense materials.



Key Engineering Materials (Volumes 284-286)

Main Theme:

Edited by:

Panjian Li, Kai Zhang and Clifford W. Colwell, Jr.




A.C. Queiroz et al., "Porous HA Scaffolds for Drug Releasing ", Key Engineering Materials, Vols. 284-286, pp. 407-410, 2005

Online since:

April 2005




[1] AC Queiroz et al., Biomaterials 22 (2001) p.1393.

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