Preparation of Vaterite/Poly(lactic acid) Composites with Excellent Apatite-Forming Ability

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A new type of ceramic-polymer biomaterial having excellent apatite-forming ability in simulated body fluid (SBF) was prepared by hot-pressing a mixture consisting of poly(-L-lactic acid)(PLA) and calcium carbonate (vaterite). The composite containing 30% vaterite showed no brittle fracture behavior and comparably high bending strength of ~50 MPa. Apatite layer of several micrometers in thickness formed on its surface after soaking in SBF at 37°C only for 1 day. Osteoclast culture tests showed that the composite coated with apatite has excellent bioresorbability. After incubation of human osteoblasts, mineralized bone nodule formation was seen on the surface.

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Periodical:

Key Engineering Materials (Volumes 284-286)

Main Theme:

Edited by:

Panjian Li, Kai Zhang and Clifford W. Colwell, Jr.

Pages:

449-452

Citation:

T. Kasuga et al., "Preparation of Vaterite/Poly(lactic acid) Composites with Excellent Apatite-Forming Ability ", Key Engineering Materials, Vols. 284-286, pp. 449-452, 2005

Online since:

April 2005

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$38.00

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