Using X-Ray Micro-CT Imaging to Monitor Dissolution of Macroporous Bioactive Glass Scaffolds

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Bioactive glass scaffolds with interconnected macroporous networks have been developed by foaming sol-gel derived bioactive glass of the 70S30C (70 mol% SiO2, 30 mol% CaO) composition. The effect of sintering temperature on the dissolution of the scaffolds in simulated body fluid (SBF) was investigated in 3D using x-ray micro-computer tomography (micro CT) and inductive coupled plasma (ICP) analysis. Micro-CT is non-destructive and allows observation of specific parts of the scaffold at various stages of degradation. However, data analysis is complex at present. Percentage porosity data obtained by micro-CT was compared to physical data and pore size distributions obtained from mercury intrusion porosimetry were compared to the interconnected pore diameters observed from the micro CT images.

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Periodical:

Key Engineering Materials (Volumes 284-286)

Main Theme:

Edited by:

Panjian Li, Kai Zhang and Clifford W. Colwell, Jr.

Pages:

493-496

Citation:

J. R. Jones et al., "Using X-Ray Micro-CT Imaging to Monitor Dissolution of Macroporous Bioactive Glass Scaffolds ", Key Engineering Materials, Vols. 284-286, pp. 493-496, 2005

Online since:

April 2005

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$38.00

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