In Vitro Cytotoxicity of Alginate-Encapsulating Ferrite Particles Using WST-1

Abstract:

Article Preview

The purpose of this study was to evaluate the cytotoxicity of alginate-encapsulting ferrite particles in vitro. Various ferrite particles such as Ba-ferrite, Sr-ferrite, Co-ferrite, Co/Ni-ferrite were prepared by sol-gel process. Ferrite particles were encapsulated via calcium alginate process with different alginate contents ranged from 10 to 100 wt%. Mouse-fibroblastic NCTC L-929 cells were cultured in RPMI-1640 medium with 10% fetal bovine serum. The alginate-encapsulating ferrites were extracted in 5 ml of distilled water under pH 6.5 at 121°C for 1 h in accordance with ISO 10993-12. In vitro cytotoxicity was evaluated by WST-1. The results of this study indicated that the alginate-encapsulting ferrite particles affected cell viability by increasing alginate contents. Especially, alginate-encapsulating process were enhanced cell viability of ferrites such as Sr-ferrite, Co/Ni-ferrite, and Ba-Ferrite when alginate content was 10 wt%.

Info:

Periodical:

Key Engineering Materials (Volumes 284-286)

Main Theme:

Edited by:

Panjian Li, Kai Zhang and Clifford W. Colwell, Jr.

Pages:

815-818

DOI:

10.4028/www.scientific.net/KEM.284-286.815

Citation:

S. B. Lee et al., "In Vitro Cytotoxicity of Alginate-Encapsulating Ferrite Particles Using WST-1", Key Engineering Materials, Vols. 284-286, pp. 815-818, 2005

Online since:

April 2005

Export:

Price:

$35.00

[1] U.O. Hafeli et al : J. MMM. Vol. 194 (1999), p.76.

[2] Y.W. Rajesh et al : J. Super Flu. Vol. 28 (2004), p.85.

[3] R.H. Muller et al : I. J. Pharma. Vol. 138 (1996), p.85.

[4] M. Safarikova et al : J. Biotech. Vol. 105 (2003), P 255.

[5] Z. G. M. Lacava et al : Mater. Vol. 201 (1999), P 431.

In order to see related information, you need to Login.