In Vitro Biodegradability of Chitosan-Organosiloxane Hybrid Membrane

Abstract:

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Chitosan-silicate hybrid membranes were prepared using g-glycidoxy-propyltrimethoxysilane (GPSM) through a sol-gel process. The amino groups of chitosan chains were reacted with the epoxy groups of GPSM and GPSM have a function as the agent to cross-link the chitosan chains. The cross-linking degree of the hybrid membranes was determined by ninhydrin assay. Fourier-transform infrared (FT-IR) spectroscopy and 29Si cross-polarization (CP) magic-angle spinning (MAS)-NMR spectroscopy were used to assess the structure of the hybrid membranes. The biodegradability of the hybrid membranes in phosphate-buffered saline solution or lysozyme solution was investigated as a function of the GPSM concentration.

Info:

Periodical:

Key Engineering Materials (Volumes 284-286)

Main Theme:

Edited by:

Panjian Li, Kai Zhang and Clifford W. Colwell, Jr.

Pages:

823-826

DOI:

10.4028/www.scientific.net/KEM.284-286.823

Citation:

K. Tsuru et al., "In Vitro Biodegradability of Chitosan-Organosiloxane Hybrid Membrane", Key Engineering Materials, Vols. 284-286, pp. 823-826, 2005

Online since:

April 2005

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Price:

$35.00

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