Effect of Calcium Phosphate Glass Scaffold with Chitosan Membrane on the Healing of Alveolar Bone in 1 Wall Intrabony Defect in the Beagle Dogs

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This study evaluated periodontal repair and biomaterial reaction following implantation of a newly fabricated calcium phosphate block bone with chitosan membrane on the regeneration of 1-wall intrabony defects in the beagle dogs. The surgical control group received a flap operation only, while the experimental group I was treated with a chitosan nonwoven membrane only and the experimental group II was treated with a chitosan nonwoven membrane and a calcium phosphate block bone. The subjects were sacrificed 12 weeks after surgery and a comparative histometric analysis was done. No root resorption or ankylosis were observed in the experimental group. Mann-Whitney U test showed that the experimental group II produced statistically significant higher gain in connective tissue adhesion, new cementum regeneration and new bone formation. Based on histological results, the calcium phosphate block bone successfully functioned as a osteoconductive scaffold for invading cells of host.

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Periodical:

Key Engineering Materials (Volumes 284-286)

Main Theme:

Edited by:

Panjian Li, Kai Zhang and Clifford W. Colwell, Jr.

Pages:

851-854

DOI:

10.4028/www.scientific.net/KEM.284-286.851

Citation:

D.H. Min et al., "Effect of Calcium Phosphate Glass Scaffold with Chitosan Membrane on the Healing of Alveolar Bone in 1 Wall Intrabony Defect in the Beagle Dogs ", Key Engineering Materials, Vols. 284-286, pp. 851-854, 2005

Online since:

April 2005

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Price:

$35.00

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