Bioactive Glass Compositions Suitable for Repeated Heat-Treatments


Article Preview

The crystallization tendency for 30 experimental glasses in the system Na2O-K2O-MgOCaO-B2O3-P2O5-SiO2 was studied with thermal methods, DTA, HSM and XRD. The glasses were also immersed into simulated body fluid for 8 and 72 hours. The formation of the silica-rich gel and calcium phosphate layer on the glasses were analyzed with SEM. The in vitro behavior and crystallization tendency for heat-treated glasses were then related. This information is essential for choosing glass compositions that can be manufactured to desired products with controlled bioactivity for different applications. In general, glasses with low alkali content can tolerate heattreatment without crystallization but have less initial Si-gel formation ability and show less in vitro bioactivity than glasses with high alkali content.



Key Engineering Materials (Volumes 284-286)

Main Theme:

Edited by:

Panjian Li, Kai Zhang and Clifford W. Colwell, Jr.




H. Arstila et al., "Bioactive Glass Compositions Suitable for Repeated Heat-Treatments", Key Engineering Materials, Vols. 284-286, pp. 925-928, 2005

Online since:

April 2005




[1] L. L. Hench: J. Am. Ceram. Soc. Vol. 74 (1991), pp.1487-510.

[2] P. Li, Q. Yang, F. Zhang and T. Kokubo: J. Mater. Sci: Mater in Med. Vol. 3 (1992), p.452.

[3] E. D. Zanotto and M. O. Prado: Phys. Chem. Glasses Vol. 42 (2001), p.191.

[4] O. Peitl, E. D. Zanotto and Larry L. Hench: J Non-Cryst Solids Vol. 292 (2001), p.115.

[5] O. P. Filho, G. P. LaTorre and L. L. Hench: J Biomed Mater Res. Vol. 30 (1996) p.509.

[6] A. El-Ghannam, E. Hamazawy and A. Yehia: J Biomed Mater Res. Vol. 55 (2001) p.387.

[7] H. Arstila, E. Vedel, L. Hupa, H. Ylänen and M. Hupa: Key Engineering Materials Vols. 254- 256 (2004) p.67.


[8] H. Scholze: Ber. Dtsch. Keram. Ges. Vol. 39 (1962), p.63.

[9] D. Zhang, E. Vedel, L. Hupa, H. Ylänen and M. Hupa: Key Engineering Materials, accepted.

[10] M. Cable in Materials Science and Technology: A Comprehensive Treatment, Vol. 9 Ed. J. Zarzycki. VCH Verlagsgesellschaft, Weinheim (1991).

[11] H. Arstila, L. Fröberg, L. Hupa, E. Vedel, H. Ylänen and M. Hupa: Glass Technology, submitted.