Preparation and Characterization of Collagen by Hydrogel Formation Method
A kind of medical collagen was prepared by hydrogel formation method. Chemical and physical properties were investigated by FTIR, amino acid analysis, SDS-PAGE, carbohydrate content analysis, heavy metal content analysis. Degradation experiments in vivo and subsequent histological investigations were carried out to evaluate the biological performance. The results suggested that the collagen achieved is promising in tissue engineering scaffold materials for a long-term (more than 12 weeks) implantation application.
Xingdong Zhang, Junzo Tanaka, Yaoting Yu and Yasuhiko Tabata
J. Lu et al., "Preparation and Characterization of Collagen by Hydrogel Formation Method", Key Engineering Materials, Vols. 288-289, pp. 377-380, 2005