Biodegradable Polymer Scaffold for Tissue Engineering
A new method for the preparation of biodegradable porous scaffolds has been developed by using preprepared ice particulates as porogen material. A novel kind of hybrid biodegradable porous scaffold has been developed by forming collagen microsponges in the pores or interstices of a synthetic polymer sponge or mesh. A hybrid sponge of synthetic polymer, collagen and hydroxyapatite has been developed for hard tissue engineering. Bovine articular cartilage-like tissue has been engineered by culturing chondrocytes in the PLGA-collagen scaffolds.
Xingdong Zhang, Junzo Tanaka, Yaoting Yu and Yasuhiko Tabata
T. Tateishi and G. P. Chen, "Biodegradable Polymer Scaffold for Tissue Engineering", Key Engineering Materials, Vols. 288-289, pp. 59-62, 2005