Biocompatibility Evaluation of Lithium-Hydroxyapatite Composites
Fifteen different lithium-hydroxyapatite composites were tested in this work. LiHA were prepared using 0.25 %, 1 % and 2 % of lithium and five different sintering temperature 900, 1000, 1100, 1200 and 1300oC. Primary culture of osteoblasts were used to evaluate the biocompatibility of the samples, concerning to cell viability and alkaline phosphatase production. The 1% LiHA samples sintered at 1100, 1200 and 13000C showed the best results.
Takashi Nakamura, Kimihiro Yamashita and Masashi Neo
P. Valério et al., "Biocompatibility Evaluation of Lithium-Hydroxyapatite Composites", Key Engineering Materials, Vols. 309-311, pp. 1121-1124, 2006