Biological Evaluation of a Laminin–Apatite–Polymer Composite for Use in Skin Terminals
An ethylene-vinyl alcohol copolymer (EVOH) film with a laminin–apatite composite layer on its surface showed improved adhesion and compatibility to living epithelial tissue compared to untreated EVOH film. This result can be attributed to the good biocompatibility of apatite and the cell-adhesion activity of the laminin on the EVOH surface. This composite material, consisting of laminin, apatite, and EVOH, is considered a promising material for skin terminals to prevent epidermal downgrowth.
Takashi Nakamura, Kimihiro Yamashita and Masashi Neo
A. Oyane et al., "Biological Evaluation of a Laminin–Apatite–Polymer Composite for Use in Skin Terminals ", Key Engineering Materials, Vols. 309-311, pp. 1181-1184, 2006