Adhesion of a Novel Calcium Phosphate Cement to Cortical Bone and Several Common Biomaterials
In this study, we have shown that by incorporating pyrophosphoric acid into a brushite cement system, it is possible to produce a cement that exhibits adhesive tensile strengths with cortical bone, alumina, sintered hydroxyapatite and 316L stainless steel of 700 kPa. To our knowledge, this is the first report of a calcium phosphate cement formulation that exhibits such adhesive properties without the addition of an organic additive. The production of a bond between medical prostheses and bone may further widen the field of application of calcium phosphate cements, additionally the adhesive nature of the calcium phosphate cement may be a desirable ‘handling characteristic’ during reconstructive surgery.
Takashi Nakamura, Kimihiro Yamashita and Masashi Neo
L. M. Grover et al., "Adhesion of a Novel Calcium Phosphate Cement to Cortical Bone and Several Common Biomaterials ", Key Engineering Materials, Vols. 309-311, pp. 849-852, 2006