Ultrasonic Characterization of Thermal Distribution in Vicinity for a Cylindrical Thermal Lesion in a Biological Tissue

Abstract:

Article Preview

The study considers an ultrasonic characterization on the thermal distribution in vicinity for a cylindrical thermal lesion formed in a biological tissue. The cylindrical heat source is made of a standard nichrome wire with the diameter of 1 mm. The wire was inserted inside a pork muscle housed in a cuboidal container made of perspex. The heat is conducted radially outwards from the wire to the surrounding tissue. Thermal distribution near the heated wire was predicted by numerically solving a bioheat transfer function using FemLab (Comsol, Inc.). As the wire temperature was raised from the environmental temperature 20 °C to more than 80 °C in steps of 5 °C, ultrasonic B-scan images were acquired at each temperature. We assessed the feasibility of detecting the lesion boundary using changes in echogenicity, changes in centroid frequency due to attenuation, tissue moving characteristics resulting from changes in the speed of sound, and elastograms. These observations will be of use in improving ultrasonic monitoring and guiding in HIFU surgery and thermo-therapeutic process in general.

Info:

Periodical:

Key Engineering Materials (Volumes 321-323)

Edited by:

Seung-Seok Lee, Joon Hyun Lee, Ik Keun Park, Sung-Jin Song, Man Yong Choi

Pages:

1133-1138

DOI:

10.4028/www.scientific.net/KEM.321-323.1133

Citation:

M. K. Jeong et al., "Ultrasonic Characterization of Thermal Distribution in Vicinity for a Cylindrical Thermal Lesion in a Biological Tissue", Key Engineering Materials, Vols. 321-323, pp. 1133-1138, 2006

Online since:

October 2006

Export:

Price:

$38.00

[1] F. Wu et al., Extracorporeal high intensity focused ultrasound ablation in the treatment of 1038 patients with solid carcinomas in China: an overview, Ultrason. Sonochem., vol. 11, pp.149-154, (2004).

DOI: 10.1016/j.ultsonch.2004.01.011

[2] A.G. Visioli et al., Preliminary results of a phase I dose escalation clinical trial using focused ultrasound in the treatment of localized tumours, Eur. J. Ultrasound, vol. 9, pp.11-18, (1999).

DOI: 10.1016/s0929-8266(99)00009-9

[3] J.G. Lynn and T.J. Putnam, Histological and cerebral lesions produced by focused ultrasound, Amer. J. Pathol., vol. 20, pp.637-649, (1944).

[4] P. Fish, Physics and Instrumentation of Diagnostic Medical Ultrasound. New York: John Wiley & Sons, (1996).

[5] R. Maass-Moreno and C. A. Damianou, Noninvasive temperature estimation in tissue via ultrasound echo-shift. Part I. Analytical model, J. Acoust. Soc. Amer., vol. 100, no. 4, Pt. 1, pp.2514-2521, (1996).

DOI: 10.1121/1.417359

[6] F.L. Lizzi and C.X. Deng, System and method for ultrasonic harmonic imaging for therapy guidance and monitoring, US Patent 6, 726, 627, Apr. 27, (2004).

[7] A.E. Worthington, J. Trachtenberg, and M.D. Sherar, Ultrasound properties of human prostate tissue during heating, Ultrason. Med. Biol., vol. 28, no. 10, pp.1311-1318, Oct. (2002).

DOI: 10.1016/s0301-5629(02)00577-x

[8] R.J. Stafford et al., Elastographic imaging of thermal lesions in soft tissue: a preliminary study in vitro, Ultrason. Med. Biol., vol. 24, no. 9, pp.1449-1458, Dec. (1998).

[9] R. Souchon et al., Visualisation of HIFU lesions using elastography of the human prostate in vivo: preliminary results, Ultrason. Med. Biol., vol. 29, no. 7, pp.1007-1015, July (2003).

[10] N.R. Miller, J.C. Bamber, and P.M. Meaney, Fundamental limitations of noninvasive temperature imaging by means of ultrasound echo strain estimation, Ultrason. Med. Biol., vol. 28, no. 10, pp.1319-1333, Oct. (2002).

DOI: 10.1016/s0301-5629(02)00608-7

[11] H.H. Pennes, Analysis of tissue and arterial blood temperatures in the resting human forearm, J Appl. Physiol., vol. 1, no. 2, pp.93-122, Aug. (1948).

In order to see related information, you need to Login.