In this study, we proposed a process of an accelerated life testing method of 5-speed manual transmissions used in vehicles, which loads are consisted of multiple alternating loads. The entire process of an 5-speed manual transmission’s accelerated life testing method where no failures are allowed, is a process that requires an abundance of assumptions, and other factors that are estimates such as the shape parameter, beta() and the fatigue damage exponent (x). And the process is consisted of 7-step process. From the 1-setp, which is the deriving the service(use) torque and speed(rpm) profile of the transmission, to the 7-step, we could determine the accelerated life time, the accelerated torque and the accelerated speed(rpm), which are the equivalent cumulative fatigue damage. Also, we have performed accelerated life test on 5-speed manual transmission by using the following 7-step process.