Cell Repopulation in Calcium Phosphate Hybridized Tendon Graft


Article Preview

Calcium phosphate (CaP) hybridized to a whole tendon graft delayed cell repopulation in anterior cruciate ligament (ACL) reconstruction in rabbits. However, a tendon graft masked with an adhesive tape at the intra-articular (IA) portion to prevent CaP hybridization did not delay cell repopulation. Synovial tissues can adhere to the tendon graft and can invade the tendon graft masked at the IA portion. The masking induced an effect similar to that of the unhybridized tendon graft. The CaP hybridized tendon grafts masked at the IA portion showed cell repopulation 2 weeks earlier than the unmasked CaP hybridized tendon grafts.



Key Engineering Materials (Volumes 330-332)

Main Theme:

Edited by:

Xingdong Zhang, Xudong Li, Hongsong Fan, Xuanyong Liu




H. Mutsuzaki et al., "Cell Repopulation in Calcium Phosphate Hybridized Tendon Graft", Key Engineering Materials, Vols. 330-332, pp. 1161-1164, 2007

Online since:

February 2007




[1] T. Taguchi, A. Kishida and M. Akashi: Chem Lett Vol. 8 (1998), p.711.

[2] S. A. Rodeo, S. P. Arnoczky, P. A. Torzilli, C. Hidaka and R. F. Warren: J Bone Joint Surg (Am) Vol. 75 (1993), p.1795.

[3] W. A. Grana, D. M. Egle, R. Mahnken and C. W. Goodhart: Am J Sports Med Vol. 22 (1994), p.344.

[4] J. B. Kleiner, D. Amiel, R. D. Roux and W. H. Akeson: J Orthop Res Vol. 4 (1981), p.466.

[5] M. Kobayashi, N Watanabe, Y. Oshima, Y. Kajikawa, M. Kawata and T. Kubo: Am J Sports Med Vol. 33 (2005), p.1892.

[6] H. Mutsuzaki, M. Sakane, H. Nakajima, A. Ito, S. Hattori, Y. Miyanaga, N. Ochiai and J. Tanaka: J Biom Mat Res (A) Vol. 70 (2004), p.319.

[7] H. Mutsuzaki, M. Sakane, A. Ito, H. Nakajima, S. Hattori, Y. Miyanaga, J. Tanaka and N. Ochiai: Biomaterials Vol. 26 (2005), p.1027 (%).

Fetching data from Crossref.
This may take some time to load.