Molecular and Crystal Structure Characterization of Calcium-Deficient Apatite


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Calcium-deficient hydroxylapatite (CDHA) powders with Ca/P ratios from1.5 to 1.67 were synthesized by wet-chemical method. Rietveld structure refinement was performed on the X-ray diffraction data and Fourier transform infrared spectroscopy was used to characterize molecular and crystal structure of CDHA. With the decrease of Ca/P ratio, the crystallite size and crystallinity decreased, but the acid phosphate content and amount of vacancies in hydroxyapatite hexagonal structure increased. The disorder of CDHA structure increase indicated calcium-deficiency and HPO4 replacement resulted in disorder of crystal in apatite structure. The more calcium is deficient, the more disorder or imperfect in CDHA structure



Key Engineering Materials (Volumes 330-332)

Main Theme:

Edited by:

Xingdong Zhang, Xudong Li, Hongsong Fan, Xuanyong Liu




H. H. Zhou et al., "Molecular and Crystal Structure Characterization of Calcium-Deficient Apatite", Key Engineering Materials, Vols. 330-332, pp. 119-122, 2007

Online since:

February 2007




[1] C. Rey, M. Shimizu, B. Collins and M.J. Glimcher: Calcif. Tissue Int. 46 (1990), pp.384-394.

[2] H. Yang, E. Paschalls and A. Boskey: J Biopolymers. Vol. 57 (2000), pp.129-139.

[3] E. Landi, A. Tampieri, G. Celotti and S. Sprio: J. Eur. Ceram. Soc. Vol. 20 (2000), p.2377.

[4] H.P. Klug and L.E. Alexander: in X-ray procedures for Polycrystalline and amorphous materials, John Wiley & Son, (1974).

[5] E. Godocikova, P. Balaz and E. Boldizarova: Hydrometallurgy. Vol. 65 (2002), pp.83-93.

[6] L. Miller, M. Chance and R. Mendelsohn: J Biochimica et Biophysica Acta. Vol. 1527 (2001), pp.11-19.

[7] D. Magne, P. Pilet, P. Weiss and G. Daculsi: J Bone. Vol. 29 (2001), pp.547-552.