Dialysis Preparation of Zinc-Substituted Nano-Hydroxyapatite and Its Characterization


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Nano-sized zinc-substituted hydroxyapatite (nano-ZnHA) has stimulatory effect on bone formation and inhibitory effect on osteoclastic bone resorption in vivo. Nano-ZnHA with serial zinc fractions (0, 2, 5, 10 mol%) were synthesized by an improved precipitation method based on dialysis process. Transmission electron microscopy observation indicated that the increase of Zn fraction led to smaller crystallite. X-ray diffraction of the products revealed that some typical characteristic peaks of HA displayed when the Zn fraction was below 10%. Fourier transform infrared spectroscopy showed that the bending peaks of the group-OH in HA became wider with the increase of Zn fraction and it disappeared at 10 mol%. The current work demonstrated that zinc could substitute for calcium into hydroxyapatite in the limited range of composition by using dialysis process.



Key Engineering Materials (Volumes 330-332)

Main Theme:

Edited by:

Xingdong Zhang, Xudong Li, Hongsong Fan, Xuanyong Liu




S. M. Zhang et al., "Dialysis Preparation of Zinc-Substituted Nano-Hydroxyapatite and Its Characterization", Key Engineering Materials, Vols. 330-332, pp. 219-222, 2007

Online since:

February 2007




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