Synthesis of Albumin/DCP Nano-Composite Particles

Abstract:

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Highly disgregated dicalcium phosphate anhydrate (DCP) nanoparticles 240-367 nm in diameter were synthesized by a reaction between calcium carbonate and phosphoric acid. When the DCP nanoparticles were immersed in a supersaturated calcium phosphate solution containing bovine serum albumin (BSA) and ethanol, BSA/DCP nano-composite particles were synthesized through the coprecipitation of BSA on the DCP nanoparticles. BSA was firmly immobilized on the BSA/DCP nano-composite particles. The results of this study suggest that DCP nanoparticles appear to be useful as a drug delivery vehicle.

Info:

Periodical:

Key Engineering Materials (Volumes 330-332)

Main Theme:

Edited by:

Xingdong Zhang, Xudong Li, Hongsong Fan, Xuanyong Liu

Pages:

239-242

DOI:

10.4028/www.scientific.net/KEM.330-332.239

Citation:

H. Ohsawa et al., "Synthesis of Albumin/DCP Nano-Composite Particles", Key Engineering Materials, Vols. 330-332, pp. 239-242, 2007

Online since:

February 2007

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Price:

$38.00

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