Effect of Precipitation Method on Stoichiometry and Morphology of Hydroxyapatite Nanoparticles


Article Preview

This paper reports synthesis of hydroxyapatite nanoparticles by three precipitation methods. Homogeneous aqueous solution of Ca(NO3)2 and H3PO4 was used as precursor solution, and NH3•H2O was precipitator. Calcium deficient hydroxyapatite nanorods were obtained by adding the precipitator into precursor solution, near stoichiometric hydroxyapatite nanoparticles were derived from adding precursor solution into the precipitator, and smaller hydroxyapatite nanoparticles were prepared by adding precipitator and precursor solution simultaneously into a reaction vessel. The stoichiometry of hydroxyapatite was mainly affected by pH at precipitation reaction process. The crystal size and shape of hydroxyapatite particles was related to Ostwald ripening. The stoichiometry and morphology of hydroxyapatite nanoparticles can be controllable by selecting suitable coprecipitation process.



Key Engineering Materials (Volumes 330-332)

Main Theme:

Edited by:

Xingdong Zhang, Xudong Li, Hongsong Fan, Xuanyong Liu




H. B. Shi et al., "Effect of Precipitation Method on Stoichiometry and Morphology of Hydroxyapatite Nanoparticles", Key Engineering Materials, Vols. 330-332, pp. 271-274, 2007

Online since:

February 2007




[1] E. S. Ahn, N. J. Gleason, A. Nakahira and J.Y. Ying: Nano Lett. Vol. 1 (2001), p.149.

[2] L. M. Rodriguez-Lorenzo, and M. Vallet-Regi: Chem. Mater. Vol. 12 (2000), p.2460.

[3] B. L. Cushing, V. L. Kolesnichenko, and C. J. O'Connor: Chem. Rev. Vol. 33(2004), p.3893.

[4] L.B. Kong, J. Ma, and F. Boey: J. Mater. Sci. Vol. 37(2002), p.1131.

[5] K.V. Ishikawa, P.V. Ducheyne and S.V. Radin: J. Mater. Sci.: Mater. Med. Vol. 4(1993) p.105.

Fetching data from Crossref.
This may take some time to load.