Preparation and Characterization of Porous β-TCP/PLLA Composites with High β-TCP Content


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Porous β-tricalcium phosphate (β-TCP)/ Poly L-lactic acid (PLLA) composites were prepared by thermally induced phase separation method. The results showed that the composite had an interconnected pore structure with ~200μm macropores. The inorganic particle content in the composites varied from 50% to 80% and these particles were homogeneously dispersed in PLLA matrix. The composites obtained in this study could act as a promising scaffold for bone tissue engineering because of the pore structure and the mechanical properties.



Key Engineering Materials (Volumes 330-332)

Main Theme:

Edited by:

Xingdong Zhang, Xudong Li, Hongsong Fan, Xuanyong Liu




H. B. Liu et al., "Preparation and Characterization of Porous β-TCP/PLLA Composites with High β-TCP Content", Key Engineering Materials, Vols. 330-332, pp. 491-494, 2007

Online since:

February 2007




[1] B Yvonne, S Matthias, V Sebastian, SS Manuel, GF Gloria: J. Polym. Sci. Pol. Phys. Vol. 44 (2006), p.656.

[2] J Iliopoulos, GB Cornwall, RON Evans, C Manganas, KA Thomas, DC Newman, WR Walsh: J. Surg. Res. Vol. 118 (2004), p.144.

[3] CH Schugens, V Maquet, C Grandfils, R Jerome, P Teyssie: Polymer. Vol. 37 (1996), p.1027.


[4] A Prokop, A Jubel, U Hahn, M Dietershagen, M Bleidistel, C Peters: Biomaterials. Vol. 26 (2005), p.4129.


[5] Z Yang, H Yuan, W Tong, P Zou, W Chen, X Zhang: Biomaterials. Vol. 17 (1996), p.2131.

[6] AR Gazdag, JM Lane, D Glaser, MD Forster: J. Am. Acad. Orthop. Surg, Vol. 3 (1995), p.1.

[7] Y Shikinami, Y Matsusue, T Nakamura: Biomaterials. Vol. 26 (2005), p.5542.

[8] G Liang, Y Yang, S Oh, J Long, CQ Zhen, J Ran, GF Yin, DL Zhou: Biomaterials. Vol. 26 (2005), p.4265.

[9] SV Dorozhkin, M Epple: Angew. Chem. Int. Ed. Vol. 41 (2002), p.3130.

[10] WP Vande, PJ Dijkstra, BW Vande, J Feijen: J. Membr. Sci. Vol. 117 (1996), p.1.

[11] M Mulder: Preparation of synthetic membranes (Kluwer Academic Pulishers, Netherlands 1996).

[12] R Bansil, G Liao: Trends. Polym. Sci. Vol. 5 (1997), p.146.