The Influence of Bovine Serum Albumin on the Biomimetic Calcium Phosphate Coating of Bioactivated Titanium

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In this study, bovine serum albumin protein (BSA) was introduced to investigate the co-precipitation process of calcium phosphate and BSA on bioactivated Ti. Commercially pure titanium were bioactivated firstly, and then immersed in a highly supersaturated stable calcium phosphate (Ca-P) solution at three different conditions. The samples designated as Ti-C, Ti-C-CB, and Ti-C-B for control. The samples were evaluated by SEM with EDX, XRD and XPS. The co-precipitation of BSA protein and Ca-P influenced the morphology of the crystals of Ti-C-CB significantly. In terms of the immersion in the Ca-P solution containing BSA, the co-precipitation of Ca-P with BSA on the surface of Ti-C-CB was a chemical process rather than simple physical adsorption, which was most possibly achieved by the linkage of –COO− groups to Ca-P. Such coprecipitated interaction led to the formation of a tight, dense and uniform Ca-P coating.

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Periodical:

Key Engineering Materials (Volumes 330-332)

Main Theme:

Edited by:

Xingdong Zhang, Xudong Li, Hongsong Fan, Xuanyong Liu

Pages:

581-584

Citation:

Y. Wu et al., "The Influence of Bovine Serum Albumin on the Biomimetic Calcium Phosphate Coating of Bioactivated Titanium", Key Engineering Materials, Vols. 330-332, pp. 581-584, 2007

Online since:

February 2007

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$38.00

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