Precipitation of Carbonated Calcium Phosphate Powders from a Highly Supersaturated SBF Solution
Hydroxy carbonated apatite (HCA) powders were prepared by precipitation from a modified SBF solution (5x M-SBF). The ionic concentrations were 5 times higher than in human blood plasma with the exception of Mg2+ and HCO3 - concentrations that were reduced in order to accelerate crystal growth. Spheroaggregates of HCA platelets with molar (Ca+Mg)/P ratios ranging from 1.44 to 1.56 were obtained after precipitation at 50 °C. The crystallite size in c-direction was approximately 20 nm and depending on the precipitation time a CO3 2- content of 1.8 to 5.2 wt.-% was determined. Using this low temperature precipitation method, HCA powders with a high specific surface area of 83 m2/g and a composition and crystallite size close to those of the mineral phase of human bone were obtained.
Xingdong Zhang, Xudong Li, Hongsong Fan, Xuanyong Liu
I. Hofmann et al., "Precipitation of Carbonated Calcium Phosphate Powders from a Highly Supersaturated SBF Solution", Key Engineering Materials, Vols. 330-332, pp. 59-62, 2007