Apatite-Forming Ability of Pectin Gels in Simulated Body Environment


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Apatite-polymer hybrids are expected as novel bone substitutes exhibiting bone-bonding ability and mechanical performances analogous to those of natural bone. In this study, we attempted preparation of organic-inorganic hybrids from different pectins such as pectic acid, apple-derived pectin and citrus-derived pectin through apatite deposition in simulated body fluid (SBF). Pectin gels were prepared by CaCl2 treatment of aqueous solutions of pectin. Apatite-forming ability of the gels was examined in SBF. The citrus-derived pectin showed tendency to form the largest amount of the apatite in SBF.



Key Engineering Materials (Volumes 330-332)

Main Theme:

Edited by:

Xingdong Zhang, Xudong Li, Hongsong Fan, Xuanyong Liu




T. Ichibouji et al., "Apatite-Forming Ability of Pectin Gels in Simulated Body Environment", Key Engineering Materials, Vols. 330-332, pp. 675-678, 2007

Online since:

February 2007




[1] T. Kokubo, H. -M. Kim and M. Kawashita: Biomaterials Vol. 24 (2003), p.2161.

[2] M. Tanahashi and T. Matsuda: J. Biomed. Mater. Res. Vol. 34 (1997), p.305.

[3] M. Kawashita, M. Nakao, M. Minoda, H. -M. Kim, T. Beppu, T. Miyamoto, T. Kokubo and T. Nakamura: Biomaterials Vol. 24 (2003), p.2477.

[4] S.B. Cho, T. Kokubo, K. Nakanishi, N. Soga, C. Ohtsuki, T. Nakamura, T. Kitsugi and T. Yamamuro: J. Am. Ceram. Soc. Vol. 78 (1995), p.1769.

[5] T. Kokubo and H. Takadama, Biomaterials Vol. 27 (2006), p.2907.