Mechano-Chemical Synthesis of Biphasic Calcium Phosphates with the Various Ratio of HA and β-TCP


Article Preview

Biphasic calcium phosphate powders (BCP) of hydroxyapatite (HA) and tricalcium phosphate (β-TCP) with the various ratio of HA to β-TCP were prepared by utilizing mechanochemical synthesis. Calcium hydrogen-phosphate dihydrate (brushite, CaHPO4⋅2H2O) and calcium carbonate (calcite, CaCO3) powders have been chosen as the starting materials. The original Ca/P ratio of CaHPO4⋅2H2O - CaCO3 batch was set to be 1.67. A mixture of starting materials was milled using a planetary mill (ZrO2 jar and balls) with water for 3, 4, 5, 6 and 7 hrs. The XRD study of calcined powders was conducted for phase identification and for HA/β-TCP ratio as well. The phases of the calcined powders were HA and β-TCP, and the HA/β-TCP ratio varied with the milling time. The mass fraction of HA and β-TCP phases was calculated from the XRD intensities of HA and β-TCP. The ratio of the mixture milled for 4 hrs and calcined at 900°C was 85(HA):15(β-TCP) (BCP 85/15) and the content of β-TCP increased with the milling time. It is believed defective HA powder formed at relatively short period of milling time (less than 3 hrs The research revealed that nanocrystalline BCP powders could be synthesized by an employment of a medium-high energy mechanical activation at room temperatures (~25°C) without any preliminary chemical processing.



Key Engineering Materials (Volumes 330-332)

Main Theme:

Edited by:

Xingdong Zhang, Xudong Li, Hongsong Fan, Xuanyong Liu




T. R. Tadjiev et al., "Mechano-Chemical Synthesis of Biphasic Calcium Phosphates with the Various Ratio of HA and β-TCP", Key Engineering Materials, Vols. 330-332, pp. 7-10, 2007

Online since:

February 2007




[1] E.B. Nery, K.L. Lynch, J Periodontol Vol. 49(1978), p.523.

[2] R.Z. Legeros, Adv. Dent. Res. Vol. 2(1988), p.164.

[3] G. Daculsi et al. Ann Otol Rhinol Larynngol, Vol. 101(1992), p.669.

[4] R.E. Grundel, M.W. Chapman, T. Yee, D.C. Moore. Clin. Orthop. Vol. 266 (1991), p.244.

[5] J. Coreno A. et al. Optical materials Vol. 27(2005), p.1281.

[6] M. Toriyama et al. Journal of European Ceramic Society Vol. 16(1996), p.429.

[7] J. Coreno A., O. Coreno A., J.J. Cruz R., C. Rodriguez Optical materials Vol. 27(2005), p.1281.

Fetching data from Crossref.
This may take some time to load.