Collagenous Molecule Immobilization on Hydroxyapatite Surface
Collagenous molecule was successfully immobilized to hydroxyapatite (HA) surface through a molecular bridge (2-Hydroxyethyl acrylate, HEMA) that was grafted to the surface with covalent bond by gamma irradiation. Hydroxyapatite modified by atelocollagen had been characterized by several surface sensitive techniques, such as FT-IR, SEM, XPS. The investigations showed that the collagen, a bioactive macromolecule, was immobilized on the HA surface through covalent bond.
Xingdong Zhang, Xudong Li, Hongsong Fan, Xuanyong Liu
B. Jiang et al., "Collagenous Molecule Immobilization on Hydroxyapatite Surface", Key Engineering Materials, Vols. 330-332, pp. 741-744, 2007