The present work was focused on glass-alumina functionally graded materials. The samples, produced by plasma spraying, were built as multi-layered systems by depositing several layers of slightly different composition, since their alumina and glass content was progressively changed. After fabricating the graded materials, several, proper characterization techniques were set up to investigate the gradient in composition, microstructure and related performances. A particular attention was paid to the observation of the graded cross sections by scanning electron microscopy, which allowed to visualize directly the graded microstructural changes. The scanning electron microscopy (SEM) inspection was integrated with accurate mechanical measurements, such as systematic depth-sensing Vickers microindentation tests performed on the graded cross sections.