Fe3O4/Polyaniline Nanoparticles with Core-Shell Structure and their Inductive Heating Property in AC Magnetic Field
The magnetite (Fe3O4) nanoparticles were prepared by coprecipitation of Fe3+ and Fe2+ with aqueous NaOH solution. The Fe3O4/polyaniline (PANI) magnetic composite nanoparticles with core-shell structure with diameter of 30-50 nm were prepared via an in-situ polymerization of aniline in aqueous solution containing Fe3O4 magnetic fluid. The inductive heat property of Fe3O4/polyaniline composite nanoparticles in an alternating current (AC) magnetic field was investigated. The potential of Fe3O4/polyaniline nanoparticles was evaluated for localized hyperthermia treatment of cancers. The saturation magnetization Ms and coercivity Hc of Fe3O4 nanoparticles are 50.05 emu/g and 137 Oe respectively, the Fe3O4/polyaniline composite nanoparticles, 26.34 emu/g and 0 Oe. Exposed in the alternating current (AC) magnetic field for 29 min, the temperatures of physiological saline suspension containing Fe3O4 nanoparticles or Fe3O4/polyaniline composite nanoparticles are 63.6 °C and 52.4 °C respectively. The Fe3O4/polyaniline composite nanoparticles would be useful as good thermoseeds for localized hyperthermia treatment of cancers.
J.K. Kim, D.Z. Wo, L.M. Zhou, H.T. Huang, K.T. Lau and M. Wang
D. L. Zhao et al., "Fe3O4/Polyaniline Nanoparticles with Core-Shell Structure and their Inductive Heating Property in AC Magnetic Field", Key Engineering Materials, Vols. 334-335, pp. 1189-1192, 2007