Influence of Ultrasonic Irradiation Power on the Synthesis Kinetics of Nano-Hydroxyapatite Prepared by a Wet Chemical Process


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Nano-particle hydroxyapatite (HAp) was directly prepared by a wet chemical precipitation method with the aid of ultrasonic irradiation in solution using Ca(NO3)2, NH4H2PO4 and NH2CONH2 as source materials. The nano-HAp formation rate at different preparation temperatures and under different ultrasonic irradiation powers was measured and the influence of ultrasonic irradiation power on the synthesis kinetics of the nano-hydroxyapatite was investigated. It was found that the nano-HAp content increased with the increase of ultrasonic irradiation power, preparation temperature and reaction time. Under different ultrasonic irradiation power, an Arrhenius relationship was found between the nano-HAp formation rate and preparation temperature. It showed that with the increase of ultrasonic irradiation power from 100W to 200W and 300W, the synthesis activation energy of nano-HAp crystallites decrease from 63.2 KJ/mol to 59.9 KJ/mol and 48.1 kJ/mol respectively by calculation.



Key Engineering Materials (Volumes 336-338)

Edited by:

Wei Pan and Jianghong Gong




L. Y. Cao et al., "Influence of Ultrasonic Irradiation Power on the Synthesis Kinetics of Nano-Hydroxyapatite Prepared by a Wet Chemical Process", Key Engineering Materials, Vols. 336-338, pp. 2092-2095, 2007

Online since:

April 2007




[1] K.L. Burg, S. Porter and J.F. Kellam: Biomaterials Vol. 21 (2000), pp.2347-2359.

[2] A.K. Dash and G.C. Cudworth: J. Pharmacolog and Toxicolog Method Vol. 40 (1998), pp.1-12.

[3] W. Suchanek and M. Yoshimura: J. Mater. Res. Vol. 13 (1998), pp.94-117.

[4] D.M. Liu: Ceram. Int. Vol. 24 (1998), pp.441-446.

[5] G. Bezzi, G. Celotti, E. Landi, T.M.G. Torretta, I. Sopyan and A. Tampieri: Mater. Chemi. Phys. Vol. 78 (2003), pp.816-824.


[6] H.Q. Zhang, S.P. Li and Y.H. Yan: Ceram. Int. Vol. 27 (2001), pp.451-454.

[7] H.S. Liu, T.S. Chin, L.S. Lai, S.Y. Chiu, K.H. Chuang, C.S. Chang and M.T. Lui: Ceram. Int. Vol. 23 (1997), pp.19-25.

[8] M. Toriyama, A. Ravaglioli, A. Krajewski, G. Celotti and A. Piancastelli: J. Euro. Ceram. Soc. Vol. 16 (1996), pp.429-436.

[9] R. Kumar, P. Cheang and K.A. Khor: J. Mater. Process Technology Vol. 113 (2001), pp.456-462.

[10] L.Y. Cao, C.B. Zhang and J.F. Huang: Mater. Lett. Vol. 59 (2005), p.1902-(1906).

[11] P. Luo and T.G. Nieh: Mater. Sci. and Enginee: C Vol. 3 (1995), pp.75-78.

[12] S.W.K. Kweha, K.A. Khora and P. Cheang: Biomaterials Vol. 23 (2002), pp.775-85.

[13] D. Worsley and A. Mills: Ultrason. Sonachem. Vol. 3(1996), p.119.