Zonal Poisson Effect on the Chondron Deformation in Articular Cartilage under Compression

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The objective of this study was to quantify the zonal difference of the in situ chondron’s Poisson effect under different magnitudes of compression. Fluorescence immunolabeling for type VI collagen was used to identify the pericellular matrix (PCM) and chondron, and a series of fluorescent confocal images were recorded and reconstructed to form quantitative three-dimensional models. The zonal variations in the mechanical response of the chondron do not appear to be due to zonal differences in PCM properties, but rather seem to result from significant inhomogeneities in relative stiffnesses of the extracellular matrix (ECM) and PCM with depth.

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Periodical:

Key Engineering Materials (Volumes 342-343)

Edited by:

Young-Ha Kim, Chong-Su Cho, Inn-Kyu Kang, Suk Young Kim and Oh Hyeong Kwon

Pages:

133-136

Citation:

J. B. Choi "Zonal Poisson Effect on the Chondron Deformation in Articular Cartilage under Compression", Key Engineering Materials, Vols. 342-343, pp. 133-136, 2007

Online since:

July 2007

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$38.00

[1] Poole CA, Flint MH, Beaumont BW, J. Orthop. Res., Vol. 5 (1987), pp.509-522.

[2] Buschmann MD, et al., Journal of Cell Science, Vol. 108 (1995), pp.1497-1508.

[3] Fank EH, et al., Journal of Biomechanics, Vol. 33 (2000), pp.1523-1527.

[4] Smith RL, et al., Journal of Rehabilitation Research and Development, Vol. 37 (2000), pp.153-161.

[5] Guliak F, Erickson GR, Ping Ting-beall H, Biophysical Journal, Vol. 82 (2002), pp.720-727.

[6] Knight M.M., Lee D.A., Bader D.L., Biochimica et Biophysica Acta, Vol. 1405 (1998), pp.67-77.

[7] Alexopoulos LG, et al., Journal of Biomechanics, Vol. 38 (2005), pp.509-517.

[8] Youn I, et al., Osteoarthritis and Cartilage, Vol. 14 (2006), pp.889-897.

[9] Wu JZ, Herzog W, J. of Biomechanics, Vol. 35 (2002), pp.931-942.

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