The Effects of Calcium Phosphate-Chitosan Block Bone Graft on the Periodontal Regeneration in One Wall Intrabony Defects in Beagle Dogs

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This study evaluated periodontal repair and biomaterial reaction following implantation of a newly fabricated calcium phosphate chitosan block bone and chitosan membrane on the regeneration of 1- wall intrabony defects in the beagle dogs. The surgical control group received a flap operation only, while experimental group was treated with calcium phosphate chitosan block bone and/or chitosan membrane. All dogs were uneventful healing without any complication. The subjects were sacrificed 8 weeks after the experimental surgery, and a comparative histological and histometric examination was done. Chitosan membrane group significantly enhanced bone regeneration compared to control, CaP-chitosan block bone and combination group. Chitosan membrane remnants were observed in chitosan and combination group, while CaP-chitosan bone materials were resorbed completely. These results suggest that Chitosan membrnae significantly enhanced bone and cementum formation in advanced periodontal defects.

Info:

Periodical:

Key Engineering Materials (Volumes 342-343)

Edited by:

Young-Ha Kim, Chong-Su Cho, Inn-Kyu Kang, Suk Young Kim and Oh Hyeong Kwon

Pages:

393-396

Citation:

S. K. Kim et al., "The Effects of Calcium Phosphate-Chitosan Block Bone Graft on the Periodontal Regeneration in One Wall Intrabony Defects in Beagle Dogs ", Key Engineering Materials, Vols. 342-343, pp. 393-396, 2007

Online since:

July 2007

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Price:

$38.00

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DOI: https://doi.org/10.1902/jop.2005.76.10.1778

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