Preparation of Naphthalocyanine Dendrimer Loaded Polyion Complex Micelle for Photodynamic Therapy
A naphthalocyanine dendrimer (DNPcZn) was synthesized as a potential candidate of photosensitizer for photodynamic therapy. DNPcZn exhibited strong Q band absorption around 780 nm, a useful wavelength for high tissue penetration. A polyion complex (PIC) micelle (DNPcZn/m) system was formed via an electrostatic interaction of anionic DNPcZn and poly(ethylene glycol)-poly(L-lysine) block copolymers (PEG-b-PLL).
Young-Ha Kim, Chong-Su Cho, Inn-Kyu Kang, Suk Young Kim and Oh Hyeong Kwon
W. D. Jang et al., "Preparation of Naphthalocyanine Dendrimer Loaded Polyion Complex Micelle for Photodynamic Therapy", Key Engineering Materials, Vols. 342-343, pp. 465-468, 2007