Preparation of Naphthalocyanine Dendrimer Loaded Polyion Complex Micelle for Photodynamic Therapy

Abstract:

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A naphthalocyanine dendrimer (DNPcZn) was synthesized as a potential candidate of photosensitizer for photodynamic therapy. DNPcZn exhibited strong Q band absorption around 780 nm, a useful wavelength for high tissue penetration. A polyion complex (PIC) micelle (DNPcZn/m) system was formed via an electrostatic interaction of anionic DNPcZn and poly(ethylene glycol)-poly(L-lysine) block copolymers (PEG-b-PLL).

Info:

Periodical:

Key Engineering Materials (Volumes 342-343)

Edited by:

Young-Ha Kim, Chong-Su Cho, Inn-Kyu Kang, Suk Young Kim and Oh Hyeong Kwon

Pages:

465-468

DOI:

10.4028/www.scientific.net/KEM.342-343.465

Citation:

W. D. Jang et al., "Preparation of Naphthalocyanine Dendrimer Loaded Polyion Complex Micelle for Photodynamic Therapy", Key Engineering Materials, Vols. 342-343, pp. 465-468, 2007

Online since:

July 2007

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Price:

$35.00

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