Effect of Ca/P Ratio on the Dissolution of Calcium Phosphate Powders
Calcium phosphate ceramics (CPC) have been attractively used in different areas of biomedical applications, such as substances of artificial hard tissue replacement implants, drug delivery system due to their biocompatibility and bioactivity. In this work, three calcium phosphate powders between Ca/P molar ratio 1.50-1.67 were synthesized by aqueous precipitation method, using the mixture of Ca(NO3)2·4H2O and H3PO4 solutions to ammonia solution. During the precipitation reaction, Ca/P molar ratio was adjusted by controlling pH of the solution between 8.0 and 10.5 by the addition of ammonium hydroxide solution. All powders were treated at 800 oC for 2 hrs. The calcined powders were immersed in pH 7.4 distilled water at 37°C for 3 and 7 days. Decomposition and related dissolution with the various Ca/P ratios were investigated by XRD, FTIR, and TEM observation.
Young-Ha Kim, Chong-Su Cho, Inn-Kyu Kang, Suk Young Kim and Oh Hyeong Kwon
J. K. Lee et al., "Effect of Ca/P Ratio on the Dissolution of Calcium Phosphate Powders", Key Engineering Materials, Vols. 342-343, pp. 661-664, 2007