The purpose of this study was to investigate the remineralization effect of Galla Rhois and Psoralea corylifolia extracts with sodium fluoride (NaF), and interaction between the herbal extracts and NaF in dentifrice using the microbiological pH cycling model on artificial caries enamel. For the analysis, Surface hardness score of the enamel lesion on bovine teeth was measured, before and after the microbiological pH cycling sequences for 15 days. It showed that fluoride group was more higher surface hardness score than non fluoride group, and there were no significant differences among test dentifrices in each group. Thus, it is suggested that Galla Rhois and Psoralea corylifolia extracts with NaF have the remineralization effect on tooth surface. And there was no antagonistic interaction between those herbal extarcts and NaF in dentifrice.