Effect of Three-Dimensional Scaffold Geometry on Chondrocyte Adhesion

Abstract:

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This paper compares the characteristics of chondrocyte adhesion on two types of threedimensional (3-D) scaffold: types A and B. These 3-D scaffolds can be repeatedly constructed with the same dimensions using microstereolithography, a system that allows the fabrication of predesigned internal structures, such as pore size and porosity, by stacking the photopolymerized material. In tissue engineering, chondrocyte adhesion to a scaffold should have a major effect on the regeneration of cartilage. In this regard, we evaluated chondrocyte adhesion to two types of scaffold and found that chondrocyte adhesion was better on the type B scaffold than on the type A, demonstrating the importance of scaffold geometry in chondrocyte adhesion.

Info:

Periodical:

Key Engineering Materials (Volumes 342-343)

Edited by:

Young-Ha Kim, Chong-Su Cho, Inn-Kyu Kang, Suk Young Kim and Oh Hyeong Kwon

Pages:

97-100

DOI:

10.4028/www.scientific.net/KEM.342-343.97

Citation:

S. J. Lee et al., "Effect of Three-Dimensional Scaffold Geometry on Chondrocyte Adhesion", Key Engineering Materials, Vols. 342-343, pp. 97-100, 2007

Online since:

July 2007

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Price:

$35.00

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