Initial Attachment of MC3T3-E1 Cells on Nano-HAp Surfaces
The initial osteoblast like cell response to bioactive nano-sized hydroxyapatite (HAp) and bioinert zirconia was evaluated with the cell morphology by SEM and cell adhesion proteins by fluorescence microscopy. Surface roughness also measured by a confocal laser microscopy. The surface roughness and topography was almost identical among specimens. The nano-sized HAp specimens showed better initial cell adhesion and activity than bioinert zirconia ceramics.
Guy Daculsi and Pierre Layrolle
U. H. Kwon et al., "Initial Attachment of MC3T3-E1 Cells on Nano-HAp Surfaces", Key Engineering Materials, Vols. 361-363, pp. 1115-1118, 2008