Development of Alkali Containing Calcium Phosphate Cements

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Commercially available calcium phosphate cements set by precipitation of nanoapatite or brushite. The goal of this study was to elucidate the most suitable conditions for forming cements from calcium potassium sodium phosphate. Furthermore, the behaviour of these cements after immersion in SBF and/or TRIS solution was investigated. Using varying additives resulted in differences in solubility kinetics. The XRD spectra of all investigated cement compositions displayed Ca2KNa(PO4)2 after setting. However, the various cement compositions differed with respect to apatite formation when immersed in TRIS buffer in and/or SBF solution. Therefore, when investigating calcium phosphate cements we consider it necessary to clearly differentiate between the phases which form after completion of the final setting time when these materials set in air, and the phases which form in a time dependant manner after immersion in different biological fluids.

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Periodical:

Key Engineering Materials (Volumes 361-363)

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Edited by:

Guy Daculsi and Pierre Layrolle

Pages:

331-334

Citation:

R. Gildenhaar et al., "Development of Alkali Containing Calcium Phosphate Cements", Key Engineering Materials, Vols. 361-363, pp. 331-334, 2008

Online since:

November 2007

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$38.00

[1] C. Müller-Mai, Bioaktive Granulate in der Unfallchirurgie, (VNM Science Publishing, München 2003).

[2] C. Müller-Mai, G. Berger, C. Voigt, B. Bakki, U. Gross: Bioceramics 10, 1997, 53-56.

[3] C. Knabe, A. Houshmand, G. Berger et al: J. of Biomedical Materials Research: Part A, (2007).

[4] . ] C. Knabe, H. Seligmann, M. Stiller et al: Transactions 32nd Annual Meeting of the Society for Biomaterials 2007, 262.

[5] F.C.M. Driessens, M.G. Boltong, E.A.P. de Maeyer et al: Biomaterials 23 (2002) 4001-4017.

[6] G. Berger et al.: Glassy crystalline materials with high solubility, and their fabrication. German Patent No. DE 120249627. 7, (2003).

[7] G. Berger, C. Ullner, G. Neumann et al. (2006), KEM 309-311: 825-828.

[8] R. Gildenhaar, G. Berger, E. Lehmann et al. (2007), KEM 330-332: 63-66 Fig. 3: XRD spectra; with cement 45 formation of apatitic phases was only evidenced after 6 weeks of immersion in TRIS buffer solution.