Development of Injectable Calcium Phosphate Cement Adding with ZrO2
In the present study, ZrO2 was added into the injectable calcium phosphate cements (CPCs) to improve their mechanical strength. Different mass fractions of ZrO2 (5 %, 10 %, 15 %, 20%) were mixed with the powder components consisted of tricalcium phosphate (α-TCP) and hydroxyapatite (HA). Then formed the paste via adding the liquid component consisted of citric acid. The compressive strength, the injectability, the initial setting time and finial time of CPC were measured, respectively. X-ray diffraction (XRD) was employed to analyse the phase of as-prepared CPC. Scanning Electron Microscope (SEM) and Energy dispersive spertrum (EDS) were used to observe the morphology and indicate the element components of CPC. The compressive strength of ZrO2-CPC was higher than that of CPC without added ZrO2. The compressive strength got the maximal when the mass fraction of ZrO2 was 15%. It had no effect on the injectability with adding ZrO2, which were 89 % to 92 %. It had a slight down-regulation of the initial and final setting time with adding ZrO2. SEM showed that there was amounts needle-like substance in CPC, which might be related to the improvement of compressive strength of CPC. XRD showed that there were HA, a few of α-TCP and ZrO2 diffraction peaks in CPCs. The present results indicate that it is feasible to improve the compressive strength of injectable CPC via adding ZrO2.
Guy Daculsi and Pierre Layrolle
J.Y. Gong et al., "Development of Injectable Calcium Phosphate Cement Adding with ZrO2", Key Engineering Materials, Vols. 361-363, pp. 347-350, 2008